This page highlights some of the projects we have undertaken for our clients. If you would like any more information on any of these projects or would like to discuss how we can help you please contact us.

Service areas: Endocrine Disruption, REACH & CLP,

Evaluation of endocrine disrupting properties of a CoRAP listed substance

The Community Rolling Action Plan (CoRAP) under REACH lists substances for which there is an initial concern that their manufacture or use could pose risk to human health or the environment. The substance evaluation process under REACH aims to clarify these potential risks. The objective of this project was to conduct a weight of evidence review of potential endocrine disrupting properties.
Find out more

Service areas: Endocrine Disruption, REACH & CLP,

Chemical factsheets to inform business risks of potential endocrine disrupters

The objective of the project was to prepare concise factsheets for a list of chemicals that had been implicated as endocrine active or endocrine disrupting chemicals. The purpose of these factsheets was for concise internal company communication on the potential business risk of the continued use of these chemicals in their products and to enable the client to proactively manage these potential risks.
Find out more

Service areas: Plant Protection Products & Biocides, Endocrine Disruption,

Weight of evidence reviews for endocrine disrupting properties of plant protection product active substances

The European legislation on plant protection products (Regulation (EC) No. 1107/2009) sets out strict criteria for approval of active substances and includes the assessment of endocrine disrupting properties. Active substances that are endocrine disruptors will not be approved under the regulation unless there is negligible exposure to humans and non-target species.
Find out more

Service areas: REACH & CLP,

REACH Projects for Consortia and Companies

REACH (Registration, Evaluation, Authorisation and restriction of CHemicals), the European Union regulation for both new and existing chemical substances, came into force on 1st June 2007. All chemicals produced or imported into the EU in quantities above 1 tonne per year per manufacturer/importer need to be registered with the European Chemicals Agency (ECHA). Considerable technical information is required for each registration, depending on the tonnage band into which the substance falls. wca have worked on the REACH registrations of various substances, with projects covering organic and inorganic substances, including multi-constituent substances and complex UVCBs.
Find out more

Service areas: Pharmaceuticals, Toxicology & Human Health Risk Assessment,

Risk Assessment of Multiple Extractables from Components of an MDI

Metered Dose Inhalers (MDIs) are manufactured from a variety of plastic or rubber materials, and over time leaching into the active substance can occur. We undertook a risk assessment to estimate risk to human health from exposure to the MDI leachables.
Find out more

Service areas: Pharmaceuticals,

Risk Assessment of HFAs used as Propellants in Autoinjector systems

We undertook a risk assessment of hydrofluoroalkanes (HFAs) exposed intradermally or subcutaneously during autoinjection in humans using a medical device. As exposure to HFAs via this pathway is uncommon, data from other exposure pathways were considered, taking into account metabolic pathways and local and systemic effects.
Find out more

Service areas: REACH & CLP,

Data collection relating to the use of cobalt

This series of projects has been undertaken on behalf of the Cobalt REACH Consortia (CoRC) and the Cobalt Development Institute (CDI). The broad aim of the projects is to design surveys to gather data from manufacturers and importers (and occasionally also downstream users) on the uses of cobalt substances. The questions are designed to understand why the cobalt substance is often essential for a specific industrial use and the volumes used for each application.
Find out more

Service areas: Socio-economic Analysis,

Translating ERA outputs into socio-economic analysis inputs under REACH

Development of a framework to translate environmental risk assessment outputs into socio-economic analysis inputs when developing Restrictions under REACH. The aim of this project, which was undertaken for ECHA’s Risk Assessment Committee, was to develop instructive examples for translating environmental risks into environmental impacts which can be practically used to inform SEA and eventual decision
Find out more

Service areas: EU Ecolabelling,

Preparation of an ecolabel application for a cleaning product

This has involved: Linking ingredients to those on the Detergents Ingredients Database (DID) list Carrying out literature searches and data review for ingredients where sufficient data were not available on the DID list or from the company Calculating the Toxicity Factors and Degradation Factors for those ingredients not on the DID list Calculating the Critical
Find out more

Service areas: Waste Management,

Review of current European practice of MBT compost-like output

Review of current European practice of MBT compost-like output use and application to land in relation to environmental protection Mechanical-Biological Treatment (MBT) is often a key element in National Strategies for the diversion of Biodegradable Municipal Waste (BMW) from landfill. Unlike incineration, it provides flexibility in the system, which is important in those Member States
Find out more

Service areas: EQS Derivation & Implementation,

Derivation of Water Framework Directive Environmental Quality Standards

In 2005, the Department of Environment, Food, and Rural Affairs (Defra) proposed that the UKTAG Chemistry Task Team (CTT) should develop standards for certain Dangerous Substances Directive (DSD) List II substances as Annex VIII substances under the Water Framework Directive. These are substances for which EQSs are currently available, i.e. List II parameters as listed
Find out more

Service areas: REACH & CLP,

Lead Consultant on REACH for Johnson Matthey

Client Johnson Matthey’s catalyst division and the European Catalyst Manufacturers Association (ECMA) Background REACH (Registration, Evaluation, Authorisation and restriction of CHemicals), the European Union regulation for both new and existing chemical substances, came into force on 1st June 2007. All chemicals produced or imported into the EU in quantities above 1 tonne per year per
Find out more

Service areas: Bioavailability of Metals, EQS Derivation & Implementation,

Classifying waterbodies affected by abandoned metals mines under the WFD

We were commissioned by the Environment Agency of England and Wales (EA) to investigate whether conventional EQS are suitably protective of aquatic life in waterbodies impacted by abandoned metal mines, or if higher metal concentrations can be acceptable in these waterbodies. Importantly, we provided guidance on how to correctly classify these waterbodies under the Water Framework Directive.
Find out more

Service areas: EQS Derivation & Implementation,

User-friendly tool for calculating the bioavailability of metals under the WFD: bio-met.net

The bio-met project has developed a free website (bio-met.net) to guide those interested in using bioavailability-based approaches for assessing the risk of metals in the freshwater aquatic environment, particularly within the EU Water Framework Directive.
Find out more

Service areas: REACH & CLP,

REACH support for catalyst industry

wca has been lead consultant on REACH for Johnson Matthey’s catalyst division and the European Catalyst Manufacturers Association (ECMA).
Find out more

Service areas: REACH & CLP,

Higher Olefins and Poly Alpha Olefins (HOPA) REACH registration project

Client HOPA REACH Consortium Background REACH (Registration, Evaluation, Authorisation and restriction of CHemicals), the European Union regulation for both new and existing chemical substances, came into force on 1st June 2007. All chemicals produced or imported into the EU in quantities above 1 tonne per year per manufacturer/importer need to be registered with the European
Find out more

Service areas: Pharmaceuticals,

Environmental risk assessment of human medicines

Client Various confidential clients Background Article 8(3) of Directive 2001/83/EC requires the submission of an evaluation of the potential environmental risks posed by medicinal products in any new marketing authorisation application. Objectives To conduct an environmental risk assessment of human medicines. Methodology Phase 1 risk assessments were undertaken according to guidance issued by the European
Find out more

Service areas: Waste Management,

Development of a Code of Practice for using recycled organic materials in land reclamation in the UK

Client SNIFFER (Scotland and Northern Ireland Forum for Environmental Research) Background Organic matter provides stability and structure, nutrients, organic carbon and other trace elements to soil. If it is not replaced the organic matter content of the soil will decrease and soil quality will deteriorate. Organic matter can be recycled to land through a variety
Find out more